TY - GEN AU - Gao,Na AU - Zou,Dan AU - Qiao,Hai-Ling TI - Concentration-dependent inhibitory effect of Baicalin on the plasma protein binding and metabolism of chlorzoxazone, a CYP2E1 probe substrate, in rats in vitro and in vivo SN - 1932-6203 PY - 2013///0820 KW - Animals KW - Area Under Curve KW - Chlorzoxazone KW - pharmacology KW - Cross-Over Studies KW - Cytochrome P-450 CYP2E1 KW - metabolism KW - Dose-Response Relationship, Drug KW - Enzyme Inhibitors KW - Female KW - Flavonoids KW - Microsomes, Liver KW - Plant Extracts KW - Protein Binding KW - Random Allocation KW - Rats KW - Rats, Sprague-Dawley KW - Time Factors KW - Treatment Outcome N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0053038 ER -