Concentration-dependent inhibitory effect of Baicalin on the plasma protein binding and metabolism of chlorzoxazone, a CYP2E1 probe substrate, in rats in vitro and in vivo. [electronic resource]
- PloS one 2013
- e53038 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1932-6203
10.1371/journal.pone.0053038 doi
Animals Area Under Curve Chlorzoxazone--pharmacology Cross-Over Studies Cytochrome P-450 CYP2E1--metabolism Dose-Response Relationship, Drug Enzyme Inhibitors--pharmacology Female Flavonoids--pharmacology Microsomes, Liver--metabolism Plant Extracts--pharmacology Protein Binding Random Allocation Rats Rats, Sprague-Dawley Time Factors Treatment Outcome