TY - GEN AU - Barbone,Dario AU - Cheung,Priscilla AU - Battula,Sailaja AU - Busacca,Sara AU - Gray,Steven G AU - Longley,Daniel B AU - Bueno,Raphael AU - Sugarbaker,David J AU - Fennell,Dean A AU - Broaddus,V Courtney TI - Vorinostat eliminates multicellular resistance of mesothelioma 3D spheroids via restoration of Noxa expression SN - 1932-6203 PY - 2013///0627 KW - Antineoplastic Agents KW - pharmacology KW - Apoptosis KW - drug effects KW - Apoptosis Regulatory Proteins KW - metabolism KW - Bcl-2-Like Protein 11 KW - Boronic Acids KW - Bortezomib KW - Cell Line, Tumor KW - Cisplatin KW - Drug Resistance, Neoplasm KW - Drug Synergism KW - Gene Expression KW - Gene Expression Regulation, Neoplastic KW - Glutamates KW - Guanine KW - analogs & derivatives KW - Humans KW - Hydroxamic Acids KW - Membrane Proteins KW - Mesothelioma KW - Myeloid Cell Leukemia Sequence 1 Protein KW - Pemetrexed KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-bcl-2 KW - genetics KW - Pyrazines KW - Spheroids, Cellular KW - Up-Regulation KW - Vorinostat N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0052753 ER -