TY - GEN AU - Liang,Yingjian AU - Zheng,Tongsen AU - Song,Ruipeng AU - Wang,Jiabei AU - Yin,Dalong AU - Wang,Luoluo AU - Liu,Haitao AU - Tian,Lantian AU - Fang,Xiang AU - Meng,Xianzhi AU - Jiang,Hongchi AU - Liu,Jiaren AU - Liu,Lianxin TI - Hypoxia-mediated sorafenib resistance can be overcome by EF24 through Von Hippel-Lindau tumor suppressor-dependent HIF-1α inhibition in hepatocellular carcinoma SN - 1527-3350 PY - 2013///0705 KW - Animals KW - Antineoplastic Agents KW - pharmacology KW - Apoptosis KW - drug effects KW - Benzylidene Compounds KW - Carcinoma, Hepatocellular KW - drug therapy KW - Cell Line, Tumor KW - Cell Movement KW - Cell Survival KW - Drug Resistance, Neoplasm KW - Drug Therapy, Combination KW - Humans KW - Hypoxia KW - physiopathology KW - Hypoxia-Inducible Factor 1, alpha Subunit KW - antagonists & inhibitors KW - Liver Neoplasms KW - Male KW - Mice KW - Mice, Inbred BALB C KW - Mice, Nude KW - NF-kappa B KW - metabolism KW - Niacinamide KW - analogs & derivatives KW - Phenylurea Compounds KW - Piperidones KW - Sorafenib KW - Treatment Outcome KW - Von Hippel-Lindau Tumor Suppressor Protein KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1002/hep.26224 ER -