Identification of structural-kinetic and structural-thermodynamic relationships for thrombin inhibitors. [electronic resource]
- Biochemistry Jan 2013
- 613-26 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1520-4995
10.1021/bi301333z doi
Antithrombins--chemistry Azetidines--chemistry Benzylamines--chemistry Catalytic Domain Crystallography, X-Ray Drug Discovery Hirudins--chemistry Humans Hydrogen Bonding Hydrophobic and Hydrophilic Interactions Kinetics Models, Molecular Protein Binding Surface Properties Thermodynamics Thrombin--antagonists & inhibitors