TY  - GEN
AU  - Misra,Uma K
AU  - Pizzo,Salvatore V
TI  - Receptor-recognized α₂-macroglobulin binds to cell surface-associated GRP78 and activates mTORC1 and mTORC2 signaling in prostate cancer cells
SN  - 1932-6203
PY  - 2013///0610
KW  - Adaptor Proteins, Signal Transducing
KW  - metabolism
KW  - Carrier Proteins
KW  - Cell Cycle Proteins
KW  - Cell Line, Tumor
KW  - Endoplasmic Reticulum Chaperone BiP
KW  - Gene Silencing
KW  - Heat-Shock Proteins
KW  - genetics
KW  - Humans
KW  - Low Density Lipoprotein Receptor-Related Protein-1
KW  - Male
KW  - Mechanistic Target of Rapamycin Complex 1
KW  - Mechanistic Target of Rapamycin Complex 2
KW  - Models, Biological
KW  - Monomeric GTP-Binding Proteins
KW  - Multiprotein Complexes
KW  - Neuropeptides
KW  - Phosphoproteins
KW  - Phosphorylation
KW  - drug effects
KW  - Prostatic Neoplasms
KW  - Protein Binding
KW  - Protein Biosynthesis
KW  - Proto-Oncogene Proteins c-akt
KW  - RNA Interference
KW  - Rapamycin-Insensitive Companion of mTOR Protein
KW  - Ras Homolog Enriched in Brain Protein
KW  - Regulatory-Associated Protein of mTOR
KW  - Ribosomal Protein S6 Kinases
KW  - Signal Transduction
KW  - TOR Serine-Threonine Kinases
KW  - Tuberous Sclerosis Complex 2 Protein
KW  - Tumor Suppressor Proteins
KW  - alpha-Macroglobulins
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1371/journal.pone.0051735
ER  -