Misra, Uma K <br/><br/>
Receptor-recognized α₂-macroglobulin binds to cell surface-associated GRP78 and activates mTORC1 and mTORC2 signaling in prostate cancer cells.  [electronic resource] 

 -  PloS one  2012 
 - e51735 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1932-6203 
<br/><br/><label>Standard No.: </label>10.1371/journal.pone.0051735  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adaptor Proteins, Signal Transducing--metabolism<br/>Carrier Proteins--metabolism<br/>Cell Cycle Proteins<br/>Cell Line, Tumor<br/>Endoplasmic Reticulum Chaperone BiP<br/>Gene Silencing<br/>Heat-Shock Proteins--genetics<br/>Humans<br/>Low Density Lipoprotein Receptor-Related Protein-1--metabolism<br/>Male<br/>Mechanistic Target of Rapamycin Complex 1<br/>Mechanistic Target of Rapamycin Complex 2<br/>Models, Biological<br/>Monomeric GTP-Binding Proteins--metabolism<br/>Multiprotein Complexes--metabolism<br/>Neuropeptides--metabolism<br/>Phosphoproteins--metabolism<br/>Phosphorylation--drug effects<br/>Prostatic Neoplasms--genetics<br/>Protein Binding<br/>Protein Biosynthesis<br/>Proto-Oncogene Proteins c-akt--metabolism<br/>RNA Interference<br/>Rapamycin-Insensitive Companion of mTOR Protein<br/>Ras Homolog Enriched in Brain Protein<br/>Regulatory-Associated Protein of mTOR<br/>Ribosomal Protein S6 Kinases--metabolism<br/>Signal Transduction<br/>TOR Serine-Threonine Kinases--metabolism<br/>Tuberous Sclerosis Complex 2 Protein<br/>Tumor Suppressor Proteins--metabolism<br/>alpha-Macroglobulins--metabolism