TY - GEN AU - Yang,Chang AU - Davis,Jennifer L AU - Zeng,Rong AU - Vora,Paras AU - Su,Xinming AU - Collins,Lynne I AU - Vangveravong,Suwanna AU - Mach,Robert H AU - Piwnica-Worms,David AU - Weilbaecher,Katherine N AU - Faccio,Roberta AU - Novack,Deborah Veis TI - Antagonism of inhibitor of apoptosis proteins increases bone metastasis via unexpected osteoclast activation SN - 2159-8290 PY - 2013///0820 KW - Animals KW - Antineoplastic Combined Chemotherapy Protocols KW - pharmacology KW - Apoptosis KW - drug effects KW - Blotting, Western KW - Bone Density Conservation Agents KW - adverse effects KW - Bone Neoplasms KW - metabolism KW - Bone and Bones KW - Breast Neoplasms KW - drug therapy KW - Cell Line, Tumor KW - Cell Proliferation KW - Cells, Cultured KW - Diphosphonates KW - administration & dosage KW - Humans KW - Imidazoles KW - Inhibitor of Apoptosis Proteins KW - antagonists & inhibitors KW - Macrophages KW - cytology KW - Mice KW - Mice, Inbred BALB C KW - Mice, Inbred C57BL KW - Mice, Nude KW - Molecular Structure KW - Oligopeptides KW - Osteoclasts KW - Osteoporosis KW - chemically induced KW - Xenograft Model Antitumor Assays KW - Zoledronic Acid N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/2159-8290.CD-12-0271 ER -