Lesovaya, Ekaterina

Combination of a selective activator of the glucocorticoid receptor Compound A with a proteasome inhibitor as a novel strategy for chemotherapy of hematologic malignancies. [electronic resource] - Cell cycle (Georgetown, Tex.) Jan 2013 - 133-44 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1551-4005

10.4161/cc.23048 doi


Apoptosis--drug effects
Boronic Acids--therapeutic use
Bortezomib
Cell Line, Tumor
Dexamethasone--toxicity
Dimerization
Drug Synergism
Hematologic Neoplasms--drug therapy
Humans
K562 Cells
Lymphoma--drug therapy
NF-kappa B--antagonists & inhibitors
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma--drug therapy
Proteasome Inhibitors--therapeutic use
Pyrazines--therapeutic use
RNA Interference
RNA, Small Interfering--metabolism
Receptors, Glucocorticoid--agonists
Transcription Factor AP-1--antagonists & inhibitors
Transcriptional Activation
Triazoles--therapeutic use
Tumor Cells, Cultured