Gillman, Kevin W

Design, optimization, and in vivo evaluation of a series of pyridine derivatives with dual NK1 antagonism and SERT inhibition for the treatment of depression. [electronic resource] - Bioorganic & medicinal chemistry letters Jan 2013 - 407-11 p. digital

Publication Type: Journal Article

1464-3405

10.1016/j.bmcl.2012.11.094 doi


Animals
Depression--drug therapy
Disease Models, Animal
Drug Design
Gerbillinae
Inhibitory Concentration 50
Molecular Structure
Neurokinin-1 Receptor Antagonists
Pyridines--chemical synthesis
Serotonin Antagonists--chemical synthesis