TY - GEN AU - Ferguson,Brian J AU - Mansur,Daniel S AU - Peters,Nicholas E AU - Ren,Hongwei AU - Smith,Geoffrey L TI - DNA-PK is a DNA sensor for IRF-3-dependent innate immunity SN - 2050-084X PY - 2015///0514 KW - Animals KW - Cytokines KW - biosynthesis KW - DNA Repair KW - immunology KW - DNA, Viral KW - DNA-Activated Protein Kinase KW - deficiency KW - DNA-Binding Proteins KW - Embryo, Mammalian KW - Fibroblasts KW - Gene Expression Regulation KW - Herpesvirus 1, Human KW - Immunity, Innate KW - Influenza A virus KW - Interferon Regulatory Factor-3 KW - genetics KW - Interferon Type I KW - Membrane Proteins KW - Mice KW - Mice, Inbred BALB C KW - Mice, Knockout KW - Nuclear Proteins KW - Primary Cell Culture KW - Protein Serine-Threonine Kinases KW - Signal Transduction KW - V(D)J Recombination KW - Vaccinia virus N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.7554/eLife.00047 ER -