TY - GEN AU - Badr,Gamal AU - Al-Sadoon,Mohamed K AU - Abdel-Maksoud,Mostafa A AU - Rabah,Danny M AU - El-Toni,Ahmed M TI - Cellular and molecular mechanisms underlie the anti-tumor activities exerted by Walterinnesia aegyptia venom combined with silica nanoparticles against multiple myeloma cancer cell types SN - 1932-6203 PY - 2013///0603 KW - Actin Cytoskeleton KW - drug effects KW - Animals KW - Antineoplastic Agents KW - pharmacology KW - Apoptosis KW - Cell Line, Tumor KW - Cell Proliferation KW - Cell Survival KW - Chemokine CXCL12 KW - Dose-Response Relationship, Drug KW - Down-Regulation KW - Drug Screening Assays, Antitumor KW - Elapid Venoms KW - Elapidae KW - metabolism KW - Enzyme Activation KW - Humans KW - Intercellular Adhesion Molecule-1 KW - Membrane Potential, Mitochondrial KW - Multiple Myeloma KW - drug therapy KW - Nanoparticles KW - therapeutic use KW - Polymerization KW - Proto-Oncogene Proteins c-bcl-2 KW - Receptors, CXCR4 KW - Silicon Dioxide KW - chemistry KW - Time Factors N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0051661 ER -