TY - GEN AU - Park,Yoon Shin AU - David,Allan E AU - Park,Kyung Min AU - Lin,Chia-Ying AU - Than,Khoi D AU - Lee,Kyuri AU - Park,Jun Beom AU - Jo,Inho AU - Park,Ki Dong AU - Yang,Victor C TI - Controlled release of simvastatin from in situ forming hydrogel triggers bone formation in MC3T3-E1 cells SN - 1550-7416 PY - 2013///1022 KW - Animals KW - Biomarkers KW - metabolism KW - Blotting, Western KW - Bone Density Conservation Agents KW - chemistry KW - Buffers KW - Cell Differentiation KW - drug effects KW - Cell Line KW - Cell Proliferation KW - Chemistry, Pharmaceutical KW - Cross-Linking Reagents KW - Delayed-Action Preparations KW - Dose-Response Relationship, Drug KW - Drug Compounding KW - Gelatin KW - Horseradish Peroxidase KW - Hydrogels KW - Hydrogen Peroxide KW - Hydrogen-Ion Concentration KW - Kinetics KW - Matrix Metalloproteinase 13 KW - genetics KW - Mice KW - Osteoblasts KW - Osteocalcin KW - Osteogenesis KW - Polyethylene Glycols KW - Polymerase Chain Reaction KW - Simvastatin KW - Solubility KW - Technology, Pharmaceutical KW - methods KW - Tyramine KW - analogs & derivatives N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1208/s12248-012-9442-6 ER -