Park, Yoon Shin <br/><br/>
Controlled release of simvastatin from in situ forming hydrogel triggers bone formation in MC3T3-E1 cells.  [electronic resource] 

 -  The AAPS journal  Apr 2013 
 - 367-76 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1550-7416 
<br/><br/><label>Standard No.: </label>10.1208/s12248-012-9442-6  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Biomarkers--metabolism<br/>Blotting, Western<br/>Bone Density Conservation Agents--chemistry<br/>Buffers<br/>Cell Differentiation--drug effects<br/>Cell Line<br/>Cell Proliferation--drug effects<br/>Chemistry, Pharmaceutical<br/>Cross-Linking Reagents--chemistry<br/>Delayed-Action Preparations<br/>Dose-Response Relationship, Drug<br/>Drug Compounding<br/>Gelatin--chemistry<br/>Horseradish Peroxidase--chemistry<br/>Hydrogels<br/>Hydrogen Peroxide--chemistry<br/>Hydrogen-Ion Concentration<br/>Kinetics<br/>Matrix Metalloproteinase 13--genetics<br/>Mice<br/>Osteoblasts--drug effects<br/>Osteocalcin--genetics<br/>Osteogenesis--drug effects<br/>Polyethylene Glycols--chemistry<br/>Polymerase Chain Reaction<br/>Simvastatin--chemistry<br/>Solubility<br/>Technology, Pharmaceutical--methods<br/>Tyramine--analogs & derivatives