Telmisartan plus propranolol improves liver fibrosis and bile duct proliferation in the PSC-like Abcb4-/- mouse model. [electronic resource]
- Digestive diseases and sciences May 2013
- 1271-81 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1573-2568
10.1007/s10620-012-2499-3 doi
ATP Binding Cassette Transporter, Subfamily B--genetics Adrenergic beta-Antagonists--pharmacology Animals Benzimidazoles--pharmacology Benzoates--pharmacology Bile Ducts--drug effects Cholangitis, Sclerosing--drug therapy Collagen Type I--metabolism Collagen Type I, alpha 1 Chain Cytokines--metabolism Disease Models, Animal Drug Evaluation, Preclinical Drug Therapy, Combination Liver--drug effects Mice Mice, Inbred BALB C Mice, Knockout Myofibroblasts--metabolism Propranolol--pharmacology RNA, Messenger--metabolism Receptor, Angiotensin, Type 1--therapeutic use Telmisartan ATP-Binding Cassette Sub-Family B Member 4