TY  - GEN
AU  - Moore,Samantha F
AU  - van den Bosch,Marion T J
AU  - Hunter,Roger W
AU  - Sakamoto,Kei
AU  - Poole,Alastair W
AU  - Hers,Ingeborg
TI  - Dual regulation of glycogen synthase kinase 3 (GSK3)α/β by protein kinase C (PKC)α and Akt promotes thrombin-mediated integrin αIIbβ3 activation and granule secretion in platelets
SN  - 1083-351X
PY  - 2013///0419
KW  - Amino Acid Substitution
KW  - Animals
KW  - Blood Platelets
KW  - metabolism
KW  - Fibrinogen
KW  - Glycogen Synthase Kinase 3
KW  - antagonists & inhibitors
KW  - Glycogen Synthase Kinase 3 beta
KW  - Heterocyclic Compounds, 3-Ring
KW  - pharmacology
KW  - Mice
KW  - Mice, Knockout
KW  - Mutation, Missense
KW  - P-Selectin
KW  - biosynthesis
KW  - Phosphorylation
KW  - drug effects
KW  - Platelet Aggregation
KW  - Platelet Glycoprotein GPIIb-IIIa Complex
KW  - genetics
KW  - Protein Kinase C-alpha
KW  - Proto-Oncogene Proteins c-akt
KW  - Pyridines
KW  - Pyrimidines
KW  - Secretory Vesicles
KW  - Thrombin
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1074/jbc.M112.429936
ER  -