Hoekstra, Ruurdtje <br/><br/>
Phase 1 and phase 2 drug metabolism and bile acid production of HepaRG cells in a bioartificial liver in absence of dimethyl sulfoxide.  [electronic resource] 

 -  Drug metabolism and disposition: the biological fate of chemicals  Mar 2013 
 - 562-7 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1521-009X 
<br/><br/><label>Standard No.: </label>10.1124/dmd.112.049098  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aryl Hydrocarbon Hydroxylases--metabolism<br/>Bile Acids and Salts--metabolism<br/>Bilirubin--metabolism<br/>Bioreactors<br/>Biotransformation<br/>Cell Culture Techniques<br/>Cell Line<br/>Cytochrome P-450 CYP2C9<br/>Cytochrome P-450 CYP3A--metabolism<br/>Dimethyl Sulfoxide--pharmacology<br/>Glucuronosyltransferase--metabolism<br/>Hepatocytes--drug effects<br/>Humans<br/>Hydroxylation<br/>Isoenzymes<br/>Kinetics<br/>Liver, Artificial<br/>Metabolic Detoxication, Phase I<br/>Metabolic Detoxication, Phase II<br/>Rifampin--pharmacology<br/>Substrate Specificity<br/>Testosterone<br/>Tolbutamide--metabolism