TY  - GEN
AU  - Huang,Timothy Y
AU  - Michael,Sarah
AU  - Xu,Tao
AU  - Sarkeshik,Ali
AU  - Moresco,James J
AU  - Yates,John R
AU  - Masliah,Eliezer
AU  - Bokoch,Gary M
AU  - DerMardirossian,Céline
TI  - A novel Rac1 GAP splice variant relays poly-Ub accumulation signals to mediate Rac1 inactivation
SN  - 1939-4586
PY  - 2013///0723
KW  - Alzheimer Disease
KW  - metabolism
KW  - Amino Acid Sequence
KW  - Amyloid beta-Protein Precursor
KW  - Brain
KW  - Cell Membrane
KW  - enzymology
KW  - GTPase-Activating Proteins
KW  - chemistry
KW  - Gene Knockdown Techniques
KW  - HEK293 Cells
KW  - HeLa Cells
KW  - Humans
KW  - Leupeptins
KW  - pharmacology
KW  - Molecular Sequence Data
KW  - NADPH Oxidase 1
KW  - NADPH Oxidases
KW  - Phosphoric Monoester Hydrolases
KW  - Polyubiquitin
KW  - Proteasome Inhibitors
KW  - Protein Isoforms
KW  - Protein Structure, Tertiary
KW  - Protein Transport
KW  - RNA, Small Interfering
KW  - genetics
KW  - Reactive Oxygen Species
KW  - Signal Transduction
KW  - cdc42 GTP-Binding Protein
KW  - rac1 GTP-Binding Protein
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1091/mbc.E12-07-0565
ER  -