4-tert-Octylphenol stimulates the expression of cathepsins in human breast cancer cells and xenografted breast tumors of a mouse model via an estrogen receptor-mediated signaling pathway. [electronic resource]
- Toxicology Feb 2013
- 13-20 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1879-3185
10.1016/j.tox.2012.10.012 doi
Animals Breast Neoplasms--pathology Cathepsin B--genetics Cathepsin D--genetics Cell Line, Tumor Cell Proliferation--drug effects Endocrine Disruptors--administration & dosage Female Gene Expression Regulation, Neoplastic--drug effects Humans Mice Mice, Inbred BALB C Neoplasm Metastasis Phenols--administration & dosage Receptors, Estrogen--metabolism Signal Transduction--drug effects Time Factors Xenograft Model Antitumor Assays