TY - GEN AU - Somekawa-Kondo,Tomoko AU - Yamaguchi,Keitaro AU - Ishitsuka,Yoichi AU - Ito,Sachiko AU - Tanaka,Kaori AU - Irikura,Mitsuru AU - Moriuchi,Hiroshi AU - Takahama,Kazuo AU - Ando,Yukio AU - Yamazaki,Toshio AU - Irie,Tetsumi TI - Aminophylline, administered at usual doses for rodents in pharmacological studies, induces hippocampal neuronal cell injury under low tidal volume hypoxic conditions in guinea-pigs SN - 2042-7158 PY - 2013///0514 KW - Aminophylline KW - administration & dosage KW - Animals KW - Antipyrine KW - CA1 Region, Hippocampal KW - drug effects KW - Creatine Kinase, BB Form KW - blood KW - Disease Models, Animal KW - Dose-Response Relationship, Drug KW - Edaravone KW - Free Radical Scavengers KW - Glutathione KW - metabolism KW - Guinea Pigs KW - Hypoxia, Brain KW - physiopathology KW - Infusions, Intravenous KW - Lipid Peroxides KW - Male KW - Nerve Tissue Proteins KW - Neurons KW - Neurotoxicity Syndromes KW - etiology KW - Oxidative Stress KW - Phosphodiesterase Inhibitors KW - Phosphopyruvate Hydratase KW - cerebrospinal fluid KW - Purinergic P1 Receptor Antagonists KW - Theophylline N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1111/j.2042-7158.2012.01566.x ER -