TY - GEN AU - Edwards,M R AU - Regamey,N AU - Vareille,M AU - Kieninger,E AU - Gupta,A AU - Shoemark,A AU - Saglani,S AU - Sykes,A AU - Macintyre,J AU - Davies,J AU - Bossley,C AU - Bush,A AU - Johnston,S L TI - Impaired innate interferon induction in severe therapy resistant atopic asthmatic children SN - 1935-3456 PY - 2014///0116 KW - Adolescent KW - Asthma KW - genetics KW - Child KW - Child, Preschool KW - DEAD Box Protein 58 KW - DEAD-box RNA Helicases KW - Female KW - Gene Expression Regulation KW - Humans KW - Hypersensitivity, Immediate KW - Immunity, Innate KW - Immunoglobulin E KW - immunology KW - Interferon-Induced Helicase, IFIH1 KW - Interferon-beta KW - Interferon-gamma KW - Interferons KW - Interleukin-8 KW - biosynthesis KW - Lung KW - Male KW - Picornaviridae Infections KW - Poly I-C KW - administration & dosage KW - RNA, Messenger KW - Receptors, Immunologic KW - Respiratory Mucosa KW - drug effects KW - Rhinovirus KW - Time Factors KW - Toll-Like Receptor 3 N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/mi.2012.118 ER -