Toxicarioside A inhibits tumor growth and angiogenesis: involvement of TGF-β/endoglin signaling. [electronic resource]
- PloS one 2012
- e50351 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1932-6203
10.1371/journal.pone.0050351 doi
Alginates--chemistry Animals Apoptosis Cardiac Glycosides--pharmacology Cell Line, Tumor Cell Movement Cell Proliferation Dose-Response Relationship, Drug Drug Screening Assays, Antitumor Endoglin Endothelial Cells--cytology Female Glucuronic Acid--chemistry Hexuronic Acids--chemistry Intracellular Signaling Peptides and Proteins--metabolism Mice Mice, Inbred BALB C Mice, Inbred C57BL Microcirculation Models, Chemical Neoplasm Invasiveness Neoplasm Transplantation Neoplasms--pathology Neovascularization, Pathologic Phosphorylation RNA, Small Interfering--metabolism Signal Transduction Transforming Growth Factor beta--metabolism