Zang, Chuanbing <br/><br/>
Concurrent inhibition of PI3-kinase and mTOR induces cell death in diffuse large B cell lymphomas, a mechanism involving down regulation of Mcl-1.  [electronic resource] 

 -  Cancer letters  Oct 2013 
 - 288-97 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1872-7980 
<br/><br/><label>Standard No.: </label>10.1016/j.canlet.2012.11.013  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adaptor Proteins, Signal Transducing--metabolism<br/>Cell Cycle Checkpoints--drug effects<br/>Cell Cycle Proteins<br/>Cell Death--genetics<br/>Cell Line, Tumor<br/>Everolimus<br/>Gene Expression Regulation, Neoplastic--drug effects<br/>Humans<br/>Imidazoles--pharmacology<br/>Lymphoma, Large B-Cell, Diffuse--genetics<br/>Myeloid Cell Leukemia Sequence 1 Protein<br/>NF-kappa B--metabolism<br/>Phosphatidylinositol 3-Kinase--metabolism<br/>Phosphoinositide-3 Kinase Inhibitors<br/>Phosphoproteins--metabolism<br/>Phosphorylation<br/>Proto-Oncogene Proteins c-akt--metabolism<br/>Proto-Oncogene Proteins c-bcl-2--genetics<br/>Proto-Oncogene Proteins c-pim-1--metabolism<br/>Quinolines--pharmacology<br/>RNA Interference<br/>Ribosomal Protein S6 Kinases, 70-kDa--metabolism<br/>Signal Transduction<br/>Sirolimus--analogs & derivatives<br/>TOR Serine-Threonine Kinases--antagonists & inhibitors