TY  - GEN
AU  - Zhong,Hai-Jing
AU  - Yang,Hui
AU  - Chan,Daniel Shiu-Hin
AU  - Leung,Chung-Hang
AU  - Wang,Hui-Min
AU  - Ma,Dik-Lung
TI  - A metal-based inhibitor of NEDD8-activating enzyme
SN  - 1932-6203
PY  - 2013///0522
KW  - Caco-2 Cells
KW  - Cell Line, Tumor
KW  - Cell-Free System
KW  - Cyclopentanes
KW  - pharmacology
KW  - DNA-Binding Proteins
KW  - chemistry
KW  - Dimerization
KW  - Dose-Response Relationship, Drug
KW  - Humans
KW  - Inhibitory Concentration 50
KW  - Ligands
KW  - Luciferases
KW  - metabolism
KW  - Magnetic Resonance Spectroscopy
KW  - methods
KW  - Metals
KW  - Models, Chemical
KW  - Molecular Conformation
KW  - NEDD8 Protein
KW  - NF-kappa B
KW  - Protein Binding
KW  - Pyridines
KW  - Pyrimidines
KW  - Rhodium
KW  - Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
KW  - Ubiquitin-Activating Enzymes
KW  - Ubiquitins
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1371/journal.pone.0049574
ER  -