TY - GEN AU - Sperling,Reisa A AU - Karlawish,Jason AU - Johnson,Keith A TI - Preclinical Alzheimer disease-the challenges ahead SN - 1759-4766 PY - 2013///0621 KW - Aged KW - Alzheimer Disease KW - diagnosis KW - Amyloid beta-Peptides KW - analysis KW - Apolipoprotein E4 KW - genetics KW - Biomarkers KW - Brain KW - pathology KW - Disease Progression KW - Early Diagnosis KW - Early Medical Intervention KW - Genetic Markers KW - Genetic Predisposition to Disease KW - Humans KW - Neuroimaging KW - Risk Factors KW - Translational Research, Biomedical N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/nrneurol.2012.241 ER -