TY - GEN AU - Finlay,David K AU - Rosenzweig,Ella AU - Sinclair,Linda V AU - Feijoo-Carnero,Carmen AU - Hukelmann,Jens L AU - Rolf,Julia AU - Panteleyev,Andrey A AU - Okkenhaug,Klaus AU - Cantrell,Doreen A TI - PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells SN - 1540-9538 PY - 2013///0225 KW - 3-Phosphoinositide-Dependent Protein Kinases KW - Animals KW - Aryl Hydrocarbon Receptor Nuclear Translocator KW - genetics KW - CD8-Positive T-Lymphocytes KW - cytology KW - Cell Differentiation KW - physiology KW - Cell Movement KW - Chemokines KW - metabolism KW - Gene Expression Regulation KW - Glucose KW - Glycolysis KW - Hypoxia-Inducible Factor 1 KW - Hypoxia-Inducible Factor 1, alpha Subunit KW - Interleukin-2 KW - pharmacology KW - Mechanistic Target of Rapamycin Complex 1 KW - Mice KW - Mice, Inbred C57BL KW - Mice, Mutant Strains KW - Mice, Transgenic KW - Multiprotein Complexes KW - Phosphatidylinositol 3-Kinases KW - Protein Serine-Threonine Kinases KW - Proteins KW - Proto-Oncogene Proteins c-akt KW - Receptors, Antigen, T-Cell KW - Receptors, Chemokine KW - TOR Serine-Threonine Kinases N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1084/jem.20112607 ER -