TY  - GEN
AU  - Liu,Yan
AU  - Hawkins,Oriana E
AU  - Su,Yingjun
AU  - Vilgelm,Anna E
AU  - Sobolik,Tammy
AU  - Thu,Yee-Mon
AU  - Kantrow,Sara
AU  - Splittgerber,Ryan C
AU  - Short,Sarah
AU  - Amiri,Katayoun I
AU  - Ecsedy,Jeffery A
AU  - Sosman,Jeffery A
AU  - Kelley,Mark C
AU  - Richmond,Ann
TI  - Targeting aurora kinases limits tumour growth through DNA damage-mediated senescence and blockade of NF-κB impairs this drug-induced senescence
SN  - 1757-4684
PY  - 2013///0606
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Ataxia Telangiectasia Mutated Proteins
KW  - Aurora Kinases
KW  - Azepines
KW  - Benzazepines
KW  - Cell Cycle Proteins
KW  - metabolism
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - drug effects
KW  - Cellular Senescence
KW  - Checkpoint Kinase 2
KW  - DNA Damage
KW  - DNA-Binding Proteins
KW  - Humans
KW  - Melanoma, Experimental
KW  - drug therapy
KW  - Mice
KW  - Mice, Nude
KW  - NF-kappa B
KW  - antagonists & inhibitors
KW  - Polyploidy
KW  - Protein Kinase Inhibitors
KW  - Protein Serine-Threonine Kinases
KW  - Pyrimidines
KW  - Tumor Suppressor Protein p53
KW  - Tumor Suppressor Proteins
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1002/emmm.201201378
ER  -