Liu, Yan <br/><br/>
Targeting aurora kinases limits tumour growth through DNA damage-mediated senescence and blockade of NF-κB impairs this drug-induced senescence.  [electronic resource] 

 -  EMBO molecular medicine  01 2013 
 - 149-66 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. 
<br/><br/><label>ISSN: </label>1757-4684 
<br/><br/><label>Standard No.: </label>10.1002/emmm.201201378  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--pharmacology<br/>Ataxia Telangiectasia Mutated Proteins<br/>Aurora Kinases<br/>Azepines--pharmacology<br/>Benzazepines--pharmacology<br/>Cell Cycle Proteins--metabolism<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Cellular Senescence--drug effects<br/>Checkpoint Kinase 2<br/>DNA Damage<br/>DNA-Binding Proteins--metabolism<br/>Humans<br/>Melanoma, Experimental--drug therapy<br/>Mice<br/>Mice, Nude<br/>NF-kappa B--antagonists & inhibitors<br/>Polyploidy<br/>Protein Kinase Inhibitors--pharmacology<br/>Protein Serine-Threonine Kinases--antagonists & inhibitors<br/>Pyrimidines--pharmacology<br/>Tumor Suppressor Protein p53--metabolism<br/>Tumor Suppressor Proteins--metabolism<br/>Xenograft Model Antitumor Assays