TY - GEN AU - Cheng,Xinlai AU - Alborzinia,Hamed AU - Merz,Karl-Heinz AU - Steinbeisser,Herbert AU - Mrowka,Ralf AU - Scholl,Catharina AU - Kitanovic,Igor AU - Eisenbrand,Gerhard AU - Wölfl,Stefan TI - Indirubin derivatives modulate TGFβ/BMP signaling at different levels and trigger ubiquitin-mediated depletion of nonactivated R-Smads SN - 1879-1301 PY - 2013///0507 KW - Animals KW - Bone Morphogenetic Proteins KW - metabolism KW - Embryo, Nonmammalian KW - Fibroblasts KW - drug effects KW - Gene Expression Regulation, Developmental KW - HeLa Cells KW - Humans KW - Indoles KW - chemistry KW - Jurkat Cells KW - MAP Kinase Signaling System KW - Phosphorylation KW - Protein Kinase Inhibitors KW - pharmacology KW - RNA, Small Interfering KW - Signal Transduction KW - Smad Proteins, Receptor-Regulated KW - Transforming Growth Factor beta KW - Ubiquitin KW - Ubiquitin Thiolesterase KW - Xenopus KW - embryology N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.chembiol.2012.09.008 ER -