CCN2 inhibits lung cancer metastasis through promoting DAPK-dependent anoikis and inducing EGFR degradation. [electronic resource]
- Cell death and differentiation Mar 2013
- 443-55 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1476-5403
10.1038/cdd.2012.136 doi
Amino Acid Sequence Anoikis Apoptosis Regulatory Proteins--antagonists & inhibitors CSK Tyrosine-Protein Kinase Calcium-Calmodulin-Dependent Protein Kinases--antagonists & inhibitors Cell Line, Tumor Cell Movement Connective Tissue Growth Factor--metabolism Death-Associated Protein Kinases ErbB Receptors--antagonists & inhibitors Extracellular Signal-Regulated MAP Kinases--metabolism Guanine Nucleotide Exchange Factors--metabolism Humans Lung Neoplasms--metabolism Molecular Sequence Data Phosphorylation Protein Binding Protein Structure, Tertiary Proto-Oncogene Proteins c-cbl--metabolism RNA Interference RNA, Messenger--metabolism RNA, Small Interfering--metabolism Rho Guanine Nucleotide Exchange Factors Signal Transduction Ubiquitination src-Family Kinases--metabolism