Hsieh, Yi-Hsuan <br/><br/>
Histone deacetylase inhibitor suberoylanilide hydroxamic acid suppresses the pro-oncogenic effects induced by hepatitis B virus pre-S2 mutant oncoprotein and represents a potential chemopreventive agent in high-risk chronic HBV patients.  [electronic resource] 

 -  Carcinogenesis  Feb 2013 
 - 475-85 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1460-2180 
<br/><br/><label>Standard No.: </label>10.1093/carcin/bgs365  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Apoptosis--drug effects<br/>Blotting, Western<br/>COP9 Signalosome Complex<br/>Carcinoma, Hepatocellular--etiology<br/>Cell Cycle--drug effects<br/>Cell Nucleus--drug effects<br/>Cell Proliferation--drug effects<br/>Cyclin-Dependent Kinase Inhibitor p27--genetics<br/>Cytoplasm--drug effects<br/>Female<br/>Fluorescent Antibody Technique<br/>Hepatitis B Surface Antigens--genetics<br/>Hepatitis B virus--drug effects<br/>Hepatitis B, Chronic--complications<br/>Hepatocytes--cytology<br/>Histone Deacetylase Inhibitors--pharmacology<br/>Humans<br/>Hydroxamic Acids--pharmacology<br/>Immunoenzyme Techniques<br/>Immunoprecipitation<br/>Intracellular Signaling Peptides and Proteins--genetics<br/>Liver Neoplasms--etiology<br/>Male<br/>Mice<br/>Mice, Inbred C57BL<br/>Mice, Transgenic<br/>Mutant Proteins--genetics<br/>Mutation--genetics<br/>Nuclear Proteins--genetics<br/>Peptide Hydrolases--genetics<br/>Protein Precursors--genetics<br/>RNA, Messenger--genetics<br/>Real-Time Polymerase Chain Reaction<br/>Reverse Transcriptase Polymerase Chain Reaction<br/>TATA Box Binding Protein-Like Proteins--genetics<br/>Two-Hybrid System Techniques<br/>Vorinostat