Lee, Chunja

The role of cytochrome P450-dependent metabolism in the regulation of mouse hepatic growth hormone signaling components and target genes by 3-methylcholanthrene. [electronic resource] - Drug metabolism and disposition: the biological fate of chemicals Feb 2013 - 457-65 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1521-009X

10.1124/dmd.112.048835 doi


Animals
Basic Helix-Loop-Helix Transcription Factors--agonists
Cytochrome P-450 Enzyme System--genetics
Gene Expression Regulation, Enzymologic
Growth Hormone--metabolism
Inflammation Mediators--metabolism
Isoenzymes
Janus Kinase 2--drug effects
Liver--drug effects
Male
Methylcholanthrene--pharmacology
Mice
Mice, Inbred C57BL
Mice, Knockout
Microsomes, Liver--drug effects
NADPH-Ferrihemoprotein Reductase--deficiency
RNA, Messenger--metabolism
Receptors, Aryl Hydrocarbon--agonists
Receptors, Somatotropin--drug effects
STAT5 Transcription Factor--genetics
Signal Transduction--drug effects
Time Factors