TY  - GEN
AU  - Varco-Merth,Benjamin
AU  - Feigerlová,Eva
AU  - Shinde,Ujwal
AU  - Rosenfeld,Ron G
AU  - Hwa,Vivian
AU  - Rotwein,Peter
TI  - Severe growth deficiency is associated with STAT5b mutations that disrupt protein folding and activity
SN  - 1944-9917
PY  - 2013///0607
KW  - Animals
KW  - Base Sequence
KW  - COS Cells
KW  - Cell Nucleus
KW  - metabolism
KW  - Chlorocebus aethiops
KW  - Growth Disorders
KW  - genetics
KW  - Growth Hormone
KW  - physiology
KW  - Humans
KW  - Mice
KW  - Models, Molecular
KW  - Mutation, Missense
KW  - Phosphorylation
KW  - Protein Binding
KW  - Protein Folding
KW  - Protein Processing, Post-Translational
KW  - Protein Stability
KW  - Protein Structure, Quaternary
KW  - Protein Structure, Secondary
KW  - Protein Transport
KW  - Rats
KW  - Receptors, Somatotropin
KW  - STAT5 Transcription Factor
KW  - chemistry
KW  - Structural Homology, Protein
KW  - Thermodynamics
KW  - Transcriptional Activation
KW  - src Homology Domains
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1210/me.2012-1275
ER  -