TY  - GEN
AU  - Kirby,Stephen D
AU  - Norris,Joseph R
AU  - Richard Smith,J
AU  - Bahnson,Brian J
AU  - Cerasoli,Douglas M
TI  - Human paraoxonase double mutants hydrolyze V and G class organophosphorus nerve agents
SN  - 1872-7786
PY  - 2013///0528
KW  - Amino Acid Substitution
KW  - Antidotes
KW  - metabolism
KW  - Aryldialkylphosphatase
KW  - chemistry
KW  - Catalytic Domain
KW  - genetics
KW  - Chemical Warfare Agents
KW  - classification
KW  - Humans
KW  - Hydrolysis
KW  - Kinetics
KW  - Models, Molecular
KW  - Mutagenesis, Site-Directed
KW  - Mutant Proteins
KW  - Organophosphates
KW  - Organophosphorus Compounds
KW  - Organothiophosphorus Compounds
KW  - Paraoxon
KW  - Protein Engineering
KW  - Recombinant Proteins
KW  - Sarin
KW  - Soman
KW  - Substrate Specificity
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1016/j.cbi.2012.10.023
ER  -