TY - GEN AU - Chen,John W AU - Figueiredo,Jose-Luiz AU - Wojtkiewicz,Gregory R AU - Siegel,Cory AU - Iwamoto,Yoshiko AU - Kim,Dong-Eog AU - Nolte,Marc W AU - Dickneite,Gerhard AU - Weissleder,Ralph AU - Nahrendorf,Matthias TI - Selective factor XIIa inhibition attenuates silent brain ischemia: application of molecular imaging targeting coagulation pathway SN - 1876-7591 PY - 2013///0509 KW - Animals KW - Anticoagulants KW - pharmacology KW - Asymptomatic Diseases KW - Blood Coagulation KW - drug effects KW - Blood Proteins KW - Brain KW - diagnostic imaging KW - Cerebral Infarction KW - blood KW - Diffusion Magnetic Resonance Imaging KW - Disease Models, Animal KW - Factor XIII KW - metabolism KW - Factor XIIa KW - antagonists & inhibitors KW - Inflammation Mediators KW - Insect Proteins KW - Mice KW - Mice, Inbred BALB C KW - Molecular Imaging KW - methods KW - Multimodal Imaging KW - Peroxidase KW - Positron-Emission Tomography KW - Recombinant Proteins KW - Time Factors KW - Tomography, X-Ray Computed N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.jcmg.2012.01.025 ER -