TY  - GEN
AU  - Azuma,Junichi
AU  - Ohno,Masako
AU  - Kubota,Ryuji
AU  - Yokota,Soichiro
AU  - Nagai,Takayuki
AU  - Tsuyuguchi,Kazunari
AU  - Okuda,Yasuhisa
AU  - Takashima,Tetsuya
AU  - Kamimura,Sayaka
AU  - Fujio,Yasushi
AU  - Kawase,Ichiro
TI  - NAT2 genotype guided regimen reduces isoniazid-induced liver injury and early treatment failure in the 6-month four-drug standard treatment of tuberculosis: a randomized controlled trial for pharmacogenetics-based therapy
SN  - 1432-1041
PY  - 2013///1119
KW  - Adult
KW  - Animals
KW  - Antitubercular Agents
KW  - adverse effects
KW  - Arylamine N-Acetyltransferase
KW  - genetics
KW  - Asian People
KW  - Chemical and Drug Induced Liver Injury
KW  - Genetic Predisposition to Disease
KW  - Genotype
KW  - Humans
KW  - Isoniazid
KW  - Male
KW  - Middle Aged
KW  - Precision Medicine
KW  - methods
KW  - Treatment Failure
KW  - Tuberculosis
KW  - drug therapy
N1  - Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1007/s00228-012-1429-9
ER  -