Azuma, Junichi

NAT2 genotype guided regimen reduces isoniazid-induced liver injury and early treatment failure in the 6-month four-drug standard treatment of tuberculosis: a randomized controlled trial for pharmacogenetics-based therapy. [electronic resource] - European journal of clinical pharmacology May 2013 - 1091-101 p. digital

Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

1432-1041

10.1007/s00228-012-1429-9 doi


Adult
Animals
Antitubercular Agents--adverse effects
Arylamine N-Acetyltransferase--genetics
Asian People--genetics
Chemical and Drug Induced Liver Injury--genetics
Genetic Predisposition to Disease--genetics
Genotype
Humans
Isoniazid--adverse effects
Male
Middle Aged
Precision Medicine--methods
Treatment Failure
Tuberculosis--drug therapy