TY - GEN AU - Singh,Jagdeep K AU - Farnie,Gillian AU - Bundred,Nigel J AU - Simões,Bruno M AU - Shergill,Amrita AU - Landberg,Göran AU - Howell,Sacha J AU - Clarke,Robert B TI - Targeting CXCR1/2 significantly reduces breast cancer stem cell activity and increases the efficacy of inhibiting HER2 via HER2-dependent and -independent mechanisms SN - 1557-3265 PY - 2013///0715 KW - Breast Neoplasms KW - genetics KW - Cell Line, Tumor KW - ErbB Receptors KW - antagonists & inhibitors KW - Female KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Interleukin-8 KW - metabolism KW - Neoplasm Grading KW - Neoplasm Metastasis KW - Neoplastic Stem Cells KW - RNA Interference KW - Receptor, ErbB-2 KW - Receptors, Interleukin-8A KW - Receptors, Interleukin-8B KW - Signal Transduction KW - Spheroids, Cellular KW - Tumor Cells, Cultured N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/1078-0432.CCR-12-1063 ER -