Singh, Jagdeep K

Targeting CXCR1/2 significantly reduces breast cancer stem cell activity and increases the efficacy of inhibiting HER2 via HER2-dependent and -independent mechanisms. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research Feb 2013 - 643-56 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1557-3265

10.1158/1078-0432.CCR-12-1063 doi


Breast Neoplasms--genetics
Cell Line, Tumor
ErbB Receptors--antagonists & inhibitors
Female
Gene Expression Regulation, Neoplastic
Humans
Interleukin-8--metabolism
Neoplasm Grading
Neoplasm Metastasis
Neoplastic Stem Cells--metabolism
RNA Interference
Receptor, ErbB-2--antagonists & inhibitors
Receptors, Interleukin-8A--antagonists & inhibitors
Receptors, Interleukin-8B--antagonists & inhibitors
Signal Transduction
Spheroids, Cellular
Tumor Cells, Cultured