TY  - GEN
AU  - Mpakou,Vassiliki E
AU  - Kontsioti,Frieda
AU  - Papageorgiou,Sotiris
AU  - Spathis,Aris
AU  - Kottaridi,Christine
AU  - Girkas,Kostas
AU  - Karakitsos,Petros
AU  - Dimitriadis,George
AU  - Dervenoulas,Ioannis
AU  - Pappa,Vasiliki
TI  - Dasatinib inhibits proliferation and induces apoptosis in the KASUMI-1 cell line bearing the t(8;21)(q22;q22) and the N822K c-kit mutation
SN  - 1873-5835
PY  - 2013///0311
KW  - Apoptosis
KW  - drug effects
KW  - Caspases
KW  - metabolism
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Chromosomes, Human, Pair 21
KW  - Chromosomes, Human, Pair 8
KW  - Dasatinib
KW  - Enzyme Activation
KW  - Humans
KW  - K562 Cells
KW  - Leukemia, Myeloid, Acute
KW  - genetics
KW  - Mutation
KW  - Phosphorylation
KW  - Protein Isoforms
KW  - Protein Kinase Inhibitors
KW  - pharmacology
KW  - Proto-Oncogene Proteins c-akt
KW  - Proto-Oncogene Proteins c-kit
KW  - Pyrimidines
KW  - Thiazoles
KW  - Translocation, Genetic
KW  - src-Family Kinases
KW  - antagonists & inhibitors
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.leukres.2012.10.011
ER  -