Mpakou, Vassiliki E <br/><br/>
Dasatinib inhibits proliferation and induces apoptosis in the KASUMI-1 cell line bearing the t(8;21)(q22;q22) and the N822K c-kit mutation.  [electronic resource] 

 -  Leukemia research  Feb 2013 
 - 175-82 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1873-5835 
<br/><br/><label>Standard No.: </label>10.1016/j.leukres.2012.10.011  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Apoptosis--drug effects<br/>Caspases--metabolism<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Chromosomes, Human, Pair 21<br/>Chromosomes, Human, Pair 8<br/>Dasatinib<br/>Enzyme Activation--drug effects<br/>Humans<br/>K562 Cells<br/>Leukemia, Myeloid, Acute--genetics<br/>Mutation<br/>Phosphorylation--drug effects<br/>Protein Isoforms<br/>Protein Kinase Inhibitors--pharmacology<br/>Proto-Oncogene Proteins c-akt--metabolism<br/>Proto-Oncogene Proteins c-kit--genetics<br/>Pyrimidines--pharmacology<br/>Thiazoles--pharmacology<br/>Translocation, Genetic<br/>src-Family Kinases--antagonists & inhibitors