Kandasamy, Jeyakumar <br/><br/>
Increased selectivity toward cytoplasmic versus mitochondrial ribosome confers improved efficiency of synthetic aminoglycosides in fixing damaged genes: a strategy for treatment of genetic diseases caused by nonsense mutations.  [electronic resource] 

 -  Journal of medicinal chemistry  Dec 2012 
 - 10630-43 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/jm3012992  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aminoglycosides--pharmacology<br/>Codon, Nonsense<br/>Cytoplasm--drug effects<br/>Genetic Diseases, Inborn--therapy<br/>Humans<br/>Magnetic Resonance Spectroscopy<br/>Mitochondria--drug effects<br/>Ribosomes--drug effects<br/>Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization