TY - GEN AU - He,Yongzheng AU - Rhodes,Steven D AU - Chen,Shi AU - Wu,Xiaohua AU - Yuan,Jin AU - Yang,Xianlin AU - Jiang,Li AU - Li,Xianqi AU - Takahashi,Naoyuki AU - Xu,Mingjiang AU - Mohammad,Khalid S AU - Guise,Theresa A AU - Yang,Feng-Chun TI - c-Fms signaling mediates neurofibromatosis Type-1 osteoclast gain-in-functions SN - 1932-6203 PY - 2013///0422 KW - Animals KW - Bone Resorption KW - drug therapy KW - Cell Adhesion KW - drug effects KW - Cell Movement KW - Cells, Cultured KW - Enzyme Inhibitors KW - therapeutic use KW - Extracellular Signal-Regulated MAP Kinases KW - metabolism KW - Female KW - Gene Deletion KW - Humans KW - Macrophage Colony-Stimulating Factor KW - Mice KW - Mice, Inbred C57BL KW - Neurofibromin 1 KW - genetics KW - Osteoclasts KW - cytology KW - Osteoporosis KW - Receptor, Macrophage Colony-Stimulating Factor KW - antagonists & inhibitors KW - Ribosomal Protein S6 Kinases, 90-kDa KW - Signal Transduction N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1371/journal.pone.0046900 ER -