Kudo, Toshiyuki <br/><br/>
Analysis of the repaglinide concentration increase produced by gemfibrozil and itraconazole based on the inhibition of the hepatic uptake transporter and metabolic enzymes.  [electronic resource] 

 -  Drug metabolism and disposition: the biological fate of chemicals  Feb 2013 
 - 362-71 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1521-009X 
<br/><br/><label>Standard No.: </label>10.1124/dmd.112.049460  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Area Under Curve<br/>Aryl Hydrocarbon Hydroxylases--antagonists & inhibitors<br/>Biotransformation<br/>Carbamates--blood<br/>Computer Simulation<br/>Cytochrome P-450 CYP2C8<br/>Cytochrome P-450 CYP3A--metabolism<br/>Cytochrome P-450 CYP3A Inhibitors<br/>Drug Interactions<br/>Enzyme Inhibitors--blood<br/>Gemfibrozil--blood<br/>Glucuronides--pharmacology<br/>Humans<br/>Hypoglycemic Agents--blood<br/>Itraconazole--blood<br/>Least-Squares Analysis<br/>Liver--drug effects<br/>Liver-Specific Organic Anion Transporter 1<br/>Models, Biological<br/>Nonlinear Dynamics<br/>Organic Anion Transporters--antagonists & inhibitors<br/>Piperidines--blood