Postexposure application of Fas receptor small-interfering RNA to suppress sulfur mustard-induced apoptosis in human airway epithelial cells: implication for a therapeutic approach. [electronic resource]
- The Journal of pharmacology and experimental therapeutics Jan 2013
- 308-16 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
1521-0103
10.1124/jpet.112.199935 doi
Animals Apoptosis--drug effects Blotting, Western Bronchoalveolar Lavage Fluid--chemistry Burns, Inhalation--drug therapy Caspase 3--metabolism Cell Line Cells, Cultured Chemical Warfare Agents--toxicity Enzyme Activation--physiology Enzyme-Linked Immunosorbent Assay Epithelial Cells--drug effects Fas Ligand Protein--analysis Flow Cytometry Humans Male Mustard Gas--toxicity RNA, Small Interfering--pharmacology Rats Rats, Sprague-Dawley Respiratory System--cytology Transfection fas Receptor--antagonists & inhibitors