TY  - GEN
AU  - Kazuki,Yasuhiro
AU  - Kobayashi,Kaoru
AU  - Aueviriyavit,Sasitorn
AU  - Oshima,Takeshi
AU  - Kuroiwa,Yoshimi
AU  - Tsukazaki,Yasuko
AU  - Senda,Naoto
AU  - Kawakami,Hiroki
AU  - Ohtsuki,Sumio
AU  - Abe,Satoshi
AU  - Takiguchi,Masato
AU  - Hoshiya,Hidetoshi
AU  - Kajitani,Naoyo
AU  - Takehara,Shoko
AU  - Kubo,Kinya
AU  - Terasaki,Tetsuya
AU  - Chiba,Kan
AU  - Tomizuka,Kazuma
AU  - Oshimura,Mitsuo
TI  - Trans-chromosomic mice containing a human CYP3A cluster for prediction of xenobiotic metabolism in humans
SN  - 1460-2083
PY  - 2013///0701
KW  - Animals
KW  - Aryl Hydrocarbon Hydroxylases
KW  - genetics
KW  - Blotting, Southern
KW  - CHO Cells
KW  - Cell Line
KW  - Chromosomes, Artificial, Human
KW  - Chromosomes, Human, Pair 7
KW  - Cloning, Molecular
KW  - Cricetinae
KW  - Cytochrome P-450 CYP3A
KW  - Dehydroepiandrosterone
KW  - metabolism
KW  - Female
KW  - Gene Expression Regulation, Enzymologic
KW  - Genetic Loci
KW  - Humans
KW  - Inactivation, Metabolic
KW  - Intestines
KW  - enzymology
KW  - Liver
KW  - Mice
KW  - Mice, Inbred ICR
KW  - Mice, Transgenic
KW  - Microsomes
KW  - Multigene Family
KW  - Triazolam
KW  - pharmacokinetics
KW  - Xenobiotics
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1093/hmg/dds468
ER  -