Kazuki, Yasuhiro <br/><br/>
Trans-chromosomic mice containing a human CYP3A cluster for prediction of xenobiotic metabolism in humans.  [electronic resource] 

 -  Human molecular genetics  Feb 2013 
 - 578-92 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1460-2083 
<br/><br/><label>Standard No.: </label>10.1093/hmg/dds468  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Aryl Hydrocarbon Hydroxylases--genetics<br/>Blotting, Southern<br/>CHO Cells<br/>Cell Line<br/>Chromosomes, Artificial, Human<br/>Chromosomes, Human, Pair 7<br/>Cloning, Molecular<br/>Cricetinae<br/>Cytochrome P-450 CYP3A--genetics<br/>Dehydroepiandrosterone--metabolism<br/>Female<br/>Gene Expression Regulation, Enzymologic<br/>Genetic Loci<br/>Humans<br/>Inactivation, Metabolic<br/>Intestines--enzymology<br/>Liver--enzymology<br/>Mice<br/>Mice, Inbred ICR<br/>Mice, Transgenic<br/>Microsomes--metabolism<br/>Multigene Family<br/>Triazolam--pharmacokinetics<br/>Xenobiotics--metabolism