TY  - GEN
AU  - Pandya,Vrajesh
AU  - Jain,Mukul
AU  - Chakrabarti,Ganes
AU  - Soni,Hitesh
AU  - Parmar,Bhavesh
AU  - Chaugule,Balaji
AU  - Patel,Jigar
AU  - Jarag,Tushar
AU  - Joshi,Jignesh
AU  - Joshi,Nirav
AU  - Rath,Akshyaya
AU  - Unadkat,Vishal
AU  - Sharma,Bhavesh
AU  - Ajani,Haresh
AU  - Kumar,Jeevan
AU  - Sairam,Kalapatapu V V M
AU  - Patel,Harilal
AU  - Patel,Pankaj
TI  - Synthesis and structure-activity relationship of potent, selective and orally active anthranilamide-based factor Xa inhibitors: application of weakly basic sulfoximine group as novel S4 binding element
SN  - 1768-3254
PY  - 2013///0516
KW  - Animals
KW  - Anticoagulants
KW  - administration & dosage
KW  - Binding Sites
KW  - drug effects
KW  - Disease Models, Animal
KW  - Dose-Response Relationship, Drug
KW  - Factor Xa Inhibitors
KW  - Humans
KW  - Imines
KW  - chemistry
KW  - Male
KW  - Models, Molecular
KW  - Molecular Structure
KW  - Rats
KW  - Rats, Wistar
KW  - Reference Values
KW  - Serine Proteases
KW  - metabolism
KW  - Serine Proteinase Inhibitors
KW  - Structure-Activity Relationship
KW  - Sulfoxides
KW  - Venous Thrombosis
KW  - drug therapy
KW  - ortho-Aminobenzoates
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.ejmech.2012.10.005
ER  -