TY  - GEN
AU  - Wei,Pei-Chi
AU  - Hsieh,Yi-Hsuan
AU  - Su,Mei-I
AU  - Jiang,Xianzhi
AU  - Hsu,Pang-Hung
AU  - Lo,Wen-Ting
AU  - Weng,Jui-Yun
AU  - Jeng,Yung-Ming
AU  - Wang,Ju-Ming
AU  - Chen,Phang-lang
AU  - Chang,Yi-Cheng
AU  - Lee,Kuo-Fen
AU  - Tsai,Ming-Daw
AU  - Shew,Jin-Yuh
AU  - Lee,Wen-Hwa
TI  - Loss of the oxidative stress sensor NPGPx compromises GRP78 chaperone activity and induces systemic disease
SN  - 1097-4164
PY  - 2013///0219
KW  - Animals
KW  - Carrier Proteins
KW  - genetics
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Cell Survival
KW  - Cell Transformation, Neoplastic
KW  - Cysteine
KW  - DNA Damage
KW  - Disulfides
KW  - metabolism
KW  - Dose-Response Relationship, Drug
KW  - Endoplasmic Reticulum Chaperone BiP
KW  - Endoplasmic Reticulum Stress
KW  - drug effects
KW  - Fibroblasts
KW  - enzymology
KW  - Glutathione Peroxidase
KW  - Heat-Shock Proteins
KW  - Homeostasis
KW  - Humans
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - Mutagenesis, Site-Directed
KW  - Mutation
KW  - Oxidants
KW  - pharmacology
KW  - Oxidation-Reduction
KW  - Oxidative Stress
KW  - Peroxidases
KW  - Protein Binding
KW  - Protein Folding
KW  - Proteostasis Deficiencies
KW  - Reactive Oxygen Species
KW  - Signal Transduction
KW  - Time Factors
KW  - Transfection
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.molcel.2012.10.007
ER  -