Wei, Pei-Chi

Loss of the oxidative stress sensor NPGPx compromises GRP78 chaperone activity and induces systemic disease. [electronic resource] - Molecular cell Dec 2012 - 747-59 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1097-4164

10.1016/j.molcel.2012.10.007 doi


Animals
Carrier Proteins--genetics
Cell Line, Tumor
Cell Proliferation
Cell Survival
Cell Transformation, Neoplastic--genetics
Cysteine
DNA Damage
Disulfides--metabolism
Dose-Response Relationship, Drug
Endoplasmic Reticulum Chaperone BiP
Endoplasmic Reticulum Stress--drug effects
Fibroblasts--enzymology
Glutathione Peroxidase
Heat-Shock Proteins--genetics
Homeostasis
Humans
Mice
Mice, Inbred C57BL
Mice, Knockout
Mutagenesis, Site-Directed
Mutation
Oxidants--pharmacology
Oxidation-Reduction
Oxidative Stress--drug effects
Peroxidases--genetics
Protein Binding
Protein Folding
Proteostasis Deficiencies--enzymology
Reactive Oxygen Species--metabolism
Signal Transduction--drug effects
Time Factors
Transfection